Abstracts should be submitted by e-mail to Dr Francesca Giuntini (E-mail: F.Giuntini@ljmu.ac.uk) by 5 pm on Thursday 1 April 2021.

 

The abstract should be written in English using Time New Roman 12 pt for the body (around 250 words), 14 pt for the title, 12 pt for the list of authors, and 11 pt for the addresses, 2.5 cm margins all around, and in single space. The name of the person who will present the lecture should be underlined. Figures and Tables may be included, but no reference should be cited in the abstract. Organize the abstract as follows.

 

Chemopreventive phytochemicals

 

Satyajit D. Sarker*, Georgiana Zavoianu, Kenneth J. Ritchie and

Lutfun Nahar

 

Centre for Natural Products Discovery, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, James Parsons Building, Byrom Street, Liverpool L3 3AF, United Kingdom

 

*E-mail: S.Sarker@ljmu.ac.uk

 

The saying ‘prevention is better than cure’ cannot possibly be more relevant to any other diseases than when it comes to prevention of cancer. Cancer is one of the major causes of mortality and morbidity in populations world-wide, and the number of cancer sufferers is set to increase significantly in the coming years because of adverse changes in environmental conditions and life style resulting from increasing urbanisation and socio-economic changes. The currently available treatments for cancers are expensive, time-consuming, suffer from serious side-effects, and often have limited effectiveness. This situation has prompted scientists to look for dietary supplements, mainly plant-based, that can potentially prevent the occurrence of cancers. Several attempts have been made to identify phytochemicals that have cancer chemopreventive potential. However, the main emphasis has predominantly been given to food plants; non-food plants have somehow been ignored or overlooked in relation to chemoprevention. Whilst the search for new and more effective anticancer drugs will remain one of the major areas of modern drug discovery operations, the importance of finding effective cancer chemopreventive agents from plants cannot be overemphasised, especially when the huge spending in health care for the treatment of cancers comes into play. This talk will present an overview on available chemopreventive phytochemicals, their possible mechanisms of actions, and the authors’ own findings on chemopreventive agents from non-food plants, utilising the mechanistic approach of induction of Nrf2 activation as an indicator for cancer chemoprevention.

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Official Language

The conference will be held in English; no simultaneous translation will be provided.

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